A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress

BACKGROUND: Mantle cell lymphoma (MCL) is a B-cell hemopathy characterized by the t(11;14) translocation and the aberrant overexpression of cyclin D1. This results in an unrestrained cell proliferation. Other genetic alterations are common in MCL cells such as SOX11 expression, mutations of ATM and/...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Ben Younes, Khaoula, Body, Simon, Costé, Élodie, Viailly, Pierre-Julien, Miloudi, Hadjer, Coudre, Clémence, Jardin, Fabrice, Ben Aissa-Fennira, Fatma, Sola, Brigitte
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553741/
https://ncbi.nlm.nih.gov/pubmed/28797244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3530-z
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