A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress

BACKGROUND: Mantle cell lymphoma (MCL) is a B-cell hemopathy characterized by the t(11;14) translocation and the aberrant overexpression of cyclin D1. This results in an unrestrained cell proliferation. Other genetic alterations are common in MCL cells such as SOX11 expression, mutations of ATM and/...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Ben Younes, Khaoula, Body, Simon, Costé, Élodie, Viailly, Pierre-Julien, Miloudi, Hadjer, Coudre, Clémence, Jardin, Fabrice, Ben Aissa-Fennira, Fatma, Sola, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553741/
https://ncbi.nlm.nih.gov/pubmed/28797244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3530-z
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