The pattern of KRAS mutations in metastatic colorectal cancer: a retrospective audit from Sri Lanka

OBJECTIVE: Activating mutations in the KRAS gene, found in approximately 53% of metastatic colorectal cancer (mCRC) cases, can render epidermal growth factor receptor (EGFR) inhibitors ineffective. Regional differences in these mutations have been reported. This is the first study which aims to desc...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Sirisena, Nirmala Dushyanthi, Deen, Kemal, Mandawala, Dayupathi Eranda Nipunika, Herath, Pumindu, Dissanayake, Vajira Harshadeva Weerabaddana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553606/
https://ncbi.nlm.nih.gov/pubmed/28797274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2731-5
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