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N-terminal engineering of glutamyl-tRNA reductase with positive charge arginine to increase 5-aminolevulinic acid biosynthesis

Five-Aminolevulinic acid (ALA), the universal precursor of all tetrapyrroles, has various applications in medicine and agriculture industries. Glutamyl-tRNA reductase (GluTR) as the first key enzyme of C5 pathway is feedback regulated by heme, and its N-terminus plays a critical role on its stabilit...

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發表在:Bioengineered
Main Authors: Zhang, Junli, Weng, Huanjiao, Ding, Wenwen, Kang, Zhen
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553337/
https://ncbi.nlm.nih.gov/pubmed/27754792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1230572
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