High Content Screening in hESC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain

Zika virus (ZIKV) infects fetal and adult human brain, and is associated with serious neurological complications. To date, no therapeutic treatment is available to treat ZIKV infected patients. We performed a high content chemical screen using human embryonic stem cell derived cortical neuron progen...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Stem Cell
Hlavní autoři: Zhou, Ting, Tan, Lei, Cederquist, Gustav Y., Fan, Yujie, Hartley, Brigham J., Mukherjee, Suranjit, Tomishima, Mark, Brennand, Kristen J., Zhang, Qisheng, Schwartz, Robert E., Evans, Todd, Studer, Lorenz, Chen, Shuibing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553280/
https://ncbi.nlm.nih.gov/pubmed/28736217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.06.017
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky