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Thermoreversible in situ gel for subgingival delivery of simvastatin for treatment of periodontal disease

OBJECTIVE: The aim of this in vitro study was to formulate an in situ thermoreversible injectable gel with poloxamer (PM) and methylcellulose (MC) to deliver simvastatin (SMV) in a controlled manner. SUBJECTS AND METHODS: Preformulation studies (Fourier transform infrared and differential scanning c...

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Détails bibliographiques
Publié dans:Int J Pharm Investig
Auteurs principaux: Rajendran, Swaminathan, Kumar, K. Sathesh, Ramesh, S., Rao, Suresh Ranga
Format: Artigo
Langue:Inglês
Publié: Medknow Publications & Media Pvt Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553261/
https://ncbi.nlm.nih.gov/pubmed/28929053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/jphi.JPHI_26_17
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