Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques

Infant humans and rhesus macaques infected with the human or simian immunodeficiency virus (HIV or SIV), respectively, express higher viral loads and progress more rapidly to AIDS than infected adults. Activated memory CD4(+) T cells in intestinal tissues are major primary target cells for SIV/HIV i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sugimoto, Chie, Merino, Kristen M., Hasegawa, Atsuhiko, Wang, Xiaolei, Alvarez, Xavier A., Wakao, Hiroshi, Mori, Kazuyasu, Kim, Woong-Ki, Veazey, Ronald S., Didier, Elizabeth S., Kuroda, Marcelo J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553179/
https://ncbi.nlm.nih.gov/pubmed/28566378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00379-17
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