Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques

Infant humans and rhesus macaques infected with the human or simian immunodeficiency virus (HIV or SIV), respectively, express higher viral loads and progress more rapidly to AIDS than infected adults. Activated memory CD4(+) T cells in intestinal tissues are major primary target cells for SIV/HIV i...

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Udgivet i:J Virol
Main Authors: Sugimoto, Chie, Merino, Kristen M., Hasegawa, Atsuhiko, Wang, Xiaolei, Alvarez, Xavier A., Wakao, Hiroshi, Mori, Kazuyasu, Kim, Woong-Ki, Veazey, Ronald S., Didier, Elizabeth S., Kuroda, Marcelo J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553179/
https://ncbi.nlm.nih.gov/pubmed/28566378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00379-17
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