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Accuracy of DNA polymerase-alpha in copying natural DNA.

The fidelity of DNA polymerase-alpha from calf thymus (9S enzyme) in copying bacteriophage phi174am16 DNA in vitro has been determined from the frequency of production of different revertants. In the self-priming reaction we were able to measure the frequencies of base pairing mismatches during the...

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Bibliographic Details
Main Authors: Grosse, F, Krauss, G, Knill-Jones, J W, Fersht, A R
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC555315/
https://ncbi.nlm.nih.gov/pubmed/11892804
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