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Nature as a trialist? Deconstructing the analogy between Mendelian Randomization and randomized trials

Mendelian randomization (MR) studies are often described as naturally occurring randomized trials in which genetic factors are randomly assigned by nature. Conceptualizing MR studies as randomized trials has profound implications for their design, conduct, reporting, and interpretation. For example,...

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Detalhes bibliográficos
Publicado no:Epidemiology
Main Authors: Swanson, Sonja A., Tiemeier, Henning, Ikram, M. Arfan, Hernán, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552969/
https://ncbi.nlm.nih.gov/pubmed/28590373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0000000000000699
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