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Type I topoisomerase activity is required for proper chromosomal segregation in Escherichia coli

Type I DNA topoisomerases are ubiquitous enzymes involved in many aspects of DNA metabolism. Escherichia coli possesses two type I topoisomerase activities, DNA topoisomerase I (Topo I) and III (Topo III). The gene encoding Topo III (topB) can be deleted without affecting cell viability. Cells posse...

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Detalhes bibliográficos
Main Authors: Zhu, Qing, Pongpech, Pintip, DiGate, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55527/
https://ncbi.nlm.nih.gov/pubmed/11493711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171579898
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