E-M, an Engineered Endostatin with High ATPase Activity, Inhibits the Recruitment and Alternative Activation of Macrophages in Non-small Cell Lung Cancer

Endostatin recently was reported by our laboratory to possess ATPase activity that is indispensable for its anti-angiogenesis and anti-tumor effects. An engineered endostatin, E-M, which owns higher ATPase activity exhibits stronger inhibitory effects on angiogenesis. Tumor-associated macrophages (T...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xu, Min, Zhang, Shaosen, Jia, Lin, Wang, Shan, Liu, Jie, Ma, Xuhui, Wang, Chunying, Fu, Yan, Luo, Yongzhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552665/
https://ncbi.nlm.nih.gov/pubmed/28848446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00532
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