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Current understanding on the pathogenesis of polyglutamine diseases

Polyglutamine (polyQ) diseases are a family of neurodegenerative disorders including Huntington’s disease, spinobulbar muscular atrophy, dentatorubral-pallidoluysian atrophy and several spinocerebellar ataxias. polyQ diseases are caused by abnormal expansion of CAG repeats in certain genes. The expa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurosci Bull
Hauptverfasser: He, Xiao-Hui, Lin, Fang, Qin, Zheng-Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552486/
https://ncbi.nlm.nih.gov/pubmed/20502504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-0113-2
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