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An Eulerian path approach to DNA fragment assembly
For the last 20 years, fragment assembly in DNA sequencing followed the “overlap–layout–consensus” paradigm that is used in all currently available assembly tools. Although this approach proved useful in assembling clones, it faces difficulties in genomic shotgun assembly. We abandon the classical “...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55524/ https://ncbi.nlm.nih.gov/pubmed/11504945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171285098 |
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