Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells

Necrosis, apoptosis and autophagic cell death are the main cell death pathways in multicellular organisms, all with distinct and overlapping cellular and biochemical features. DNA damage may trigger different types of cell death in cancer cells but the molecular events governing the mode of cell dea...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Kutuk, Ozgur, Aytan, Nurgul, Karakas, Bahriye, Kurt, Asli Giray, Acikbas, Ufuk, Temel, Sehime Gulsun, Basaga, Huveyda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552129/
https://ncbi.nlm.nih.gov/pubmed/28796811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182809
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