Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells

Necrosis, apoptosis and autophagic cell death are the main cell death pathways in multicellular organisms, all with distinct and overlapping cellular and biochemical features. DNA damage may trigger different types of cell death in cancer cells but the molecular events governing the mode of cell dea...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kutuk, Ozgur, Aytan, Nurgul, Karakas, Bahriye, Kurt, Asli Giray, Acikbas, Ufuk, Temel, Sehime Gulsun, Basaga, Huveyda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552129/
https://ncbi.nlm.nih.gov/pubmed/28796811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182809
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