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Essential role of Drosophila Hdac1 in homeotic gene silencing

Deacetylation of the N-terminal tails of core histones plays a crucial role in gene silencing. Rpd3 and Hda1 represent two major types of genes encoding trichostatin A-sensitive histone deacetylases. Although they have been widely found, their cellular and developmental roles remain to be elucidated...

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Main Authors: Chang, Yuh-Long, Peng, Yu-Huei, Pan, I-Ching, Sun, Der-Shan, King, Balas, Huang, Der-Hwa
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC55521/
https://ncbi.nlm.nih.gov/pubmed/11493709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171325498
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