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Mesenchymal stromal cells (MSC) from JAK2(+) myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesis

There is evidence of continuous bidirectional cross-talk between malignant cells and bone marrow-derived mesenchymal stromal cells (BM-MSC), which favors the emergence and progression of myeloproliferative neoplastic (MPN) diseases. In the current work we have compared the function and gene expressi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ramos, Teresa L., Sánchez-Abarca, Luis Ignacio, Rosón-Burgo, Beatriz, Redondo, Alba, Rico, Ana, Preciado, Silvia, Ortega, Rebeca, Rodríguez, Concepción, Muntión, Sandra, Hernández-Hernández, Ángel, De Las Rivas, Javier, González, Marcos, González Porras, José Ramón, del Cañizo, Consuelo, Sánchez-Guijo, Fermín
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552029/
https://ncbi.nlm.nih.gov/pubmed/28796790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182470
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