Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.

The nucleotide sequence of four anti-(Glu60-Ala30-Tyr10)n (GAT) monoclonal gamma 1 heavy chain mRNAs was determined from codon 10 to 120. This sequence overlaps with the NH2-terminal amino acid sequence, allowing elucidation of the complete protein sequence encompassing regions VH, D and JH. These s...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Rocca-Serra, J, Matthes, H W, Kaartinen, M, Milstein, C, Thèze, J, Fougereau, M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1983
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC555202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6416834/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1983.tb01515.x
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