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The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells
Maintaining functional telomeres is important for long-term proliferation of cells. About 15% of cancer cells are telomerase-negative and activate the alternative-lengthening of telomeres (ALT) pathway to maintain their telomeres. Recent studies have shown that the human CTC1/STN1/TEN1 complex (CST)...
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| Publicado en: | Exp Cell Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551977/ https://ncbi.nlm.nih.gov/pubmed/28366536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.03.058 |
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