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Improved Gene Transfer with Functionalized Hollow Mesoporous Silica Nanoparticles of Reduced Cytotoxicity

Gene therapy is a promising strategy for treatment of genetically caused diseases. Successful gene delivery requires an efficient carrier to transfer the desired gene into host cells. Recently, mesoporous silica nanoparticles (MSNs) functionalized with 25 kD polyethyleneimine (PEI) were extensively...

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Detalhes bibliográficos
Publicado no:Materials (Basel)
Main Authors: Zhan, Zhengwen, Zhang, Xiaoxu, Huang, Jiayuan, Huang, Ying, Huang, Zhengwei, Pan, Xin, Quan, Guilan, Liu, Hu, Wang, Lili, Wu, Chuanbin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551774/
https://ncbi.nlm.nih.gov/pubmed/28773087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma10070731
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