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Phosphoinositide-dependent enrichment of actin monomers in dendritic spines regulates synapse development and plasticity

Dendritic spines are small postsynaptic compartments of excitatory synapses in the vertebrate brain that are modified during learning, aging, and neurological disorders. The formation and modification of dendritic spines depend on rapid assembly and dynamic remodeling of the actin cytoskeleton in th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Lei, Wenliang, Myers, Kenneth R., Rui, Yanfang, Hladyshau, Siarhei, Tsygankov, Denis, Zheng, James Q.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551708/
https://ncbi.nlm.nih.gov/pubmed/28659327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612042
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