Formation of Z-DNA in negatively supercoiled plasmids is sensitive to small changes in salt concentration within the physiological range.

Negative supercoiling of the plasmid pBR322 with or without an insert of (dG-dC)n induces the formation of Z-DNA as measured by the binding of antibodies specific for Z-DNA. Increasing the concentration of Na+ (or K+) is shown to inhibit the B to Z-DNA conversion. This may be due to the effect of th...

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Bibliografische gegevens

Gepubliceerd in:	EMBO J
Hoofdauteurs:	Azorin, F, Nordheim, A, Rich, A
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Publishing Group 1983
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC555164/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6315414/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1983.tb01479.x
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