Pentablock copolymer dexamethasone nanoformulations elevate MYOC: in vitro liberation, activity and safety in human trabecular meshwork cells

AIM: The aim of this study is to examine the elevation of MYOC in long-term treatment of human trabecular meshwork (HTM) cells using dexamethasone (DEX) encapsulated pentablock (PB) copolymer-based nanoparticles (NPs) (DEX-PB-NPs). MATERIALS & METHODS: PB copolymers and DEX-PB-NPs were synthesiz...

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Bibliografiske detaljer
Udgivet i:Nanomedicine (Lond)
Main Authors: Agrahari, Vibhuti, Li, Guorong, Agrahari, Vivek, Navarro, Iris, Perkumas, Kristin, Mandal, Abhirup, Stamer, W Daniel, Mitra, Ashim K
Format: Artigo
Sprog:Inglês
Udgivet: Future Medicine Ltd 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551562/
https://ncbi.nlm.nih.gov/pubmed/28756742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2017-0140
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