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The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.

We have determined the DNA sequence of the H-2Kb gene of the C57B1/10 mouse. Comparison of this sequence with that of the allelic H-2Kd shows surprisingly that the exons have accumulated more mutations than their introns. Moreover, many of these changes in the exons are clustered in short regions or...

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Detalhes bibliográficos
Main Authors: Weiss, E, Golden, L, Zakut, R, Mellor, A, Fahrner, K, Kvist, S, Flavell, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555154/
https://ncbi.nlm.nih.gov/pubmed/11894963
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