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iRGD-functionalized PEGylated nanoparticles for enhanced colon tumor accumulation and targeted drug delivery
AIM: To enhance the tumor accumulation and targeted drug delivery for colon cancer therapy, iRGD peptide was introduced to the surface of PEGylated camptothecin-loaded nanoparticles (NPs). METHODS: Cellular uptake, targeting specificity, biodistribution and antitumor capacity were evaluated. RESULTS...
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| Publicado no: | Nanomedicine (Lond) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551526/ https://ncbi.nlm.nih.gov/pubmed/28745123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2017-0107 |
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