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STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance
Leptin (LEP) binds to the long form of the leptin receptor (LEPRb), leading to activation of multiple signaling pathways that are potential targets for disrupting the obesity-breast cancer link. In triple-negative breast cancer (TNBC), LEP is hypothesized to predominantly mediate its tumorigenic eff...
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| Vydáno v: | Endocr Relat Cancer |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551450/ https://ncbi.nlm.nih.gov/pubmed/28729467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-16-0349 |
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