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Sequences involved in the regulated expression of the human interferon-beta1 gene in recombinant SV40 DNA vectors replicating in monkey cells.

The human genomic EcoRI fragment of 1.83 kb containing the interferon (IFN) gene IFN-beta1 with 285 nucleotides of 5'-flanking sequences was transfected into monkey kidney CV-1 cells as part of an SV40-pML2 vector. Induction of the monkey cells to produce IFN led to a rapid accumulation of IFN-...

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Bibliographische Detailangaben
Hauptverfasser: Maroteaux, L, Kahana, C, Mory, Y, Groner, Y, Revel, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555136/
https://ncbi.nlm.nih.gov/pubmed/11894945
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