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An Entirely SPPS-Based Strategy for Synthesis of GBAP Analogue Libraries: Investigating the Structure-Activity Relationships of the Enterococcus faecalis Quorum Sensing Signal

The development of an entirely solid-phase peptide synthesis-based synthesis of the quorum sensing signal gelatinase biosynthesis-activating pheromone (GBAP) from Enterococcus faecalis is reported. The method was used to prepare three libraries of analogues to investigate the structure-activity rela...

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Vydáno v:Org Lett
Hlavní autoři: McBrayer, Dominic N., Gantman, Brooke K., Cameron, Crissey D., Tal-Gan, Yftah
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551036/
https://ncbi.nlm.nih.gov/pubmed/28590764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01444
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