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Developmental downregulation of LIS1 expression limits axonal extension and allows axon pruning
The robust axonal growth and regenerative capacities of young neurons decrease substantially with age. This developmental downregulation of axonal growth may facilitate axonal pruning and neural circuit formation but limits functional recovery following nerve damage. While external factors influenci...
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| Publicado no: | Biol Open |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550919/ https://ncbi.nlm.nih.gov/pubmed/28630356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.025999 |
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