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Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps

Neutrophils, the most abundant type of leukocytes in blood, can form neutrophil extracellular traps (NETs). These are pathogen-trapping structures generated by expulsion of the neutrophil's DNA with associated proteolytic enzymes. NETs produced by infection can promote cancer metastasis. Here,...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Park, Juwon, Wysocki, Robert W., Amoozgar, Zohreh, Maiorino, Laura, Fein, Miriam R., Jorns, Julie, Schott, Anne F., Kinugasa-Katayama, Yumi, Lee, Youngseok, Won, Nam H., Nakasone, Elizabeth S., Hearn, Stephen A., Küttner, Victoria, Qiu, Jing, Almeida, Ana S., Perurena, Naiara, Kessenbrock, Kai, Goldberg, Michael S., Egeblad, Mikala
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550900/
https://ncbi.nlm.nih.gov/pubmed/27798263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aag1711
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