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Rapid Screening for Targeted Genetic Variants via High-Resolution Melting Curve Analysis

BACKGROUND: Current methods for the detection of single nucleotide polymorphisms (SNPs) associated with aberrant drug-metabolizing enzyme function are hindered by long turnaround times and specialized techniques and instrumentation. In this study, we describe the development and validation of a high...

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Publicat a:Clin Chem Lab Med
Autors principals: Chambliss, Allison B., Resnick, Molly, Petrides, Athena K., Clarke, William A., Marzinke, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550898/
https://ncbi.nlm.nih.gov/pubmed/27732553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/cclm-2016-0603
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