The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis

Dysregulation of the epidermal growth factor receptor (EGFR) promotes cancer cell growth, invasion and metastasis. However, its relevant downstream effectors are still limited. Here, we show that EGFR promotes breast tumor growth and metastasis by downregulating the tumor suppressor micoRNA-338-3p (...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Liang, Yingchun, Xu, Xiaojie, Wang, Tao, Li, Ying, You, Wenye, Fu, Jing, Liu, Yang, Jin, Shuai, Ji, Quanbo, Zhao, Wei, Song, Qi, Li, Ling, Hong, Tian, Huang, Junjian, Lyu, Zhaohui, Ye, Qinong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550870/
https://ncbi.nlm.nih.gov/pubmed/28703807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.325
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