Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis

Filaggrin (FLG) mutation is a well-confirmed genetic aberration in atopic dermatitis (AD). Genome-wide association studies on AD have revealed other susceptibility genes, for example, Ovo-like 1 (OVOL1). Nonetheless, the relation between FLG and OVOL1 is unclear. Because aryl hydrocarbon receptor (A...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tsuji, Gaku, Hashimoto-Hachiya, Akiko, Kiyomatsu-Oda, Mari, Takemura, Masaki, Ohno, Fumitaka, Ito, Takamichi, Morino-Koga, Saori, Mitoma, Chikage, Nakahara, Takeshi, Uchi, Hiroshi, Furue, Masutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550867/
https://ncbi.nlm.nih.gov/pubmed/28703805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.322
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