Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

Diabetic retinopathy (DR) is a well-known microvascular complication related to inflammation. Mcc950 is a potent and specific inhibitor of the NLRP3 inflammasome but its influence on DR has not been studied. Thus, we evaluated the anti-inflammatory effects of Mcc950 on high-glucose-induced human ret...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Yi, Lv, Xuehua, Hu, Zizhong, Ye, Xiaojian, Zheng, Xinhua, Ding, Yuzhi, Xie, Ping, Liu, Qinghuai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550855/
https://ncbi.nlm.nih.gov/pubmed/28726778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.308
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