Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat

Motor impairment is one of the serious side-effects of morphine, which is an exogenous agonist of the μ-opioid receptor (MOR) as well as a widely used analgesic drug in clinical practice for chronic pain treatment. Endomorphins (EMs, including EM-1 and EM-2), the most effective and specific endogeno...

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Vydáno v:Front Neural Circuits
Hlavní autoři: Wu, Zhen-Yu, Lu, Ya-Cheng, Feng, Ban, Chen, Ying-Biao, Bai, Yang, Zhang, Ting, Zhang, Hua, Chen, Tao, Dong, Yu-Ling, Li, Hui, Li, Yun-Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550698/
https://ncbi.nlm.nih.gov/pubmed/28848403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2017.00055
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