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Involvement of MAPK/ERK kinase-ERK pathway in exogenous bFGF-induced Egr-1 binding activity enhancement in anoxia-reoxygenation injured astrocytes

OBJECTIVE: Intravenous administration of basic fibroblast growth factor (bFGF) is effective to reduce the volume of cerebral infract due to ischemia. This study was designed to investigate the molecular mechanism, especially the signal transduction pathways, involved in this protective role of bFGF....

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Liu, Ying, Lu, Jin-Biao, Chen, Qi, Ye, Zhu-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550585/
https://ncbi.nlm.nih.gov/pubmed/17687397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-007-0033-y
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