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Effect of α-synuclein on the promoter activity of tyrosine hydroxylase gene
OBJECTIVE: To approach the associated mechanism by which α-synuclein (α-Syn) might regulate the metabolism of dopamine. METHODS: A DNA fragment, located at −495 to +25 of the human tyrosine hydroxylase (TH) gene, was amplified by PCR and inserted into the pGL(3)-Basic luciferase reporter vector. The...
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| Publicado no: | Neurosci Bull |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550569/ https://ncbi.nlm.nih.gov/pubmed/17592526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-007-0008-z |
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