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Single-cell profiling of lineage determining transcription factors in antigen-specific CD4(+) T cells reveals unexpected complexity in recall responses during immune reconstitution

Recent studies of protein and gene expression at the single-cell level have revealed that the memory T-cell compartment is more heterogeneous than previously acknowledged. Identifying different T helper subsets involved in memory responses at the single-cell level is thus necessary to understand the...

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Détails bibliographiques
Publié dans:Immunol Cell Biol
Auteurs principaux: Phetsouphanh, Chansavath, Xu, Yin, Munier, Mee Ling, Zaunders, John J, Kelleher, Anthony D
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550558/
https://ncbi.nlm.nih.gov/pubmed/28485382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2017.28
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