Purification of muscarinic acetylcholine receptors by affinity chromatography.

Calf forebrain homogenates contain 2.8 pM muscarinic acetylcholine receptors per mg of protein. [3H]Antagonist saturation binding experiments under equilibrium conditions revealed a single class of sites with equilibrium dissociation constants of 0.82 nM for [3H]dexetimide and 0.095 nM for [3H]quinu...

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Bibliographic Details
Main Authors: André, C, De Backer, J P, Guillet, J C, Vanderheyden, P, Vauquelin, G, Strosberg, A D
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC555051/
https://ncbi.nlm.nih.gov/pubmed/6605245
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