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IGF-1 receptor regulates dynamic changes in neuronal polarity during cerebral cortical migration

During cortical development, neurons undergo polarization, oriented migration and layer-type differentiation. The biological and biochemical mechanisms underlying these processes are not completely understood. In neurons in culture we showed that IGF-1 receptor activation is important for growth con...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Nieto Guil, Alvaro F., Oksdath, Mariana, Weiss, Linnea A., Grassi, Diego J., Sosa, Lucas J., Nieto, Marta, Quiroga, Santiago
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550468/
https://ncbi.nlm.nih.gov/pubmed/28794445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08140-5
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