Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia

Miscarriage and intrauterine growth restriction (IUGR) are devastating complications in fetal/neonatal alloimmune thrombocytopenia (FNAIT). We previously reported the mechanisms for bleeding diatheses, but it is unknown whether placental, decidual immune cells or other abnormalities at the maternal–...

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Publicado en:Nat Commun
Main Authors: Yougbaré, Issaka, Tai, Wei-She, Zdravic, Darko, Oswald, Brigitta Elaine, Lang, Sean, Zhu, Guangheng, Leong-Poi, Howard, Qu, Dawei, Yu, Lisa, Dunk, Caroline, Zhang, Jianhong, Sled, John G., Lye, Stephen J., Brkić, Jelena, Peng, Chun, Höglund, Petter, Croy, B. Anne, Adamson, S. Lee, Wen, Xiao-Yan, Stewart, Duncan J., Freedman, John, Ni, Heyu
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550461/
https://ncbi.nlm.nih.gov/pubmed/28794456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00269-1
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