Lumican delays melanoma growth in mice and drives tumor molecular assembly as well as response to matrix-targeted TAX2 therapeutic peptide

Lumican is a small leucine-rich proteoglycan (SLRP) being known as a key regulator of collagen fibrillogenesis. However, little attention has been given so far in studying its influence on tumor-associated matrix architecture. Here, we investigate the role of host lumican on tumor matrix organizatio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jeanne, Albin, Untereiner, Valérie, Perreau, Corinne, Proult, Isabelle, Gobinet, Cyril, Boulagnon-Rombi, Camille, Terryn, Christine, Martiny, Laurent, Brézillon, Stéphane, Dedieu, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550434/
https://ncbi.nlm.nih.gov/pubmed/28794454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07043-9
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