Porphyromonas gingivalis Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88

Porphyromonas gingivalis is a gram-negative anaerobic periodontal pathogen that persists in dysbiotic mixed-species biofilms alongside a dense inflammatory infiltrate of neutrophils and other leukocytes in the subgingival areas of the periodontium. Toll-like receptor 2 (TLR2) mediates the inflammato...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Makkawi, Hasnaa, Hoch, Shifra, Burns, Elia, Hosur, Kavita, Hajishengallis, George, Kirschning, Carsten J., Nussbaum, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550410/
https://ncbi.nlm.nih.gov/pubmed/28848717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00359
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