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Selenocysteine as a Latent Bioorthogonal Electrophilic Probe for Deubiquitylating Enzymes
Deubiquitylating enzymes (DUBs) remove ubiquitin (Ub) from various cellular proteins and render eukaryotic ubiquitylation a dynamic process. The misregulation of protein ubiquitylation is associated with many human diseases, and there is an urgent need to identify specific DUBs associated with thera...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550359/ https://ncbi.nlm.nih.gov/pubmed/27723317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05688 |
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