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Design of Elastic Networks with Evolutionary Optimized Long-Range Communication as Mechanical Models of Allosteric Proteins
Allosteric effects often underlie the activity of proteins, and elucidating generic design aspects and functional principles unique to allosteric phenomena represent a major challenge. Here an approach consisting of the in silico design of synthetic structures, which, as the principal element of all...
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| Publicado en: | Biophys J |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550307/ https://ncbi.nlm.nih.gov/pubmed/28793211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.043 |
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