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Nalfurafine Suppresses Pruritogen- and Touch-evoked Scratching Behavior in Models of Acute and Chronic Itch in Mice

The kappa-opioid agonist, nalfurafine, has been approved in Japan for treatment of itch in patients with chronic kidney disease. We presently investigated if systemic administration of nalfurafine inhibited ongoing or touch-evoked scratching behavior (alloknesis) following acute intradermal injectio...

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Detalhes bibliográficos
Publicado no:Acta Derm Venereol
Main Authors: AKIYAMA, Tasuku, CARSTENS, Mirela Iodi, PIECHA, Dorothea, STEPAN, Sonja, CARSTENS, Earl
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550099/
https://ncbi.nlm.nih.gov/pubmed/24890341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2340/00015555-1879
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