SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer

It has been reported that functionally distinct cancer stem cells (CSCs) exist in human bladder cancer (BCa). Here, we found that Sox2, a transcription factor that is well characterized as a marker for stem cells, is upregulated in both mouse and human BCa. Sox2 expression is absent in normal urothe...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Zhu, Fengyu, Qian, Weiqing, Zhang, Haojie, Liang, Yu, Wu, Mingqing, Zhang, Yingyin, Zhang, Xiuhong, Gao, Qian, Li, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550032/
https://ncbi.nlm.nih.gov/pubmed/28793245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.004
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