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Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma

Heterogeneity within tumors is becoming increasingly recognized as an important cause of treatment failure in cancer. Two recent studies use fate-mapping and limiting dilution transplantation assays to identify SRY (sex determining region Y)-box 2 (Sox2) as cancer stem-cell marker and driver of canc...

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Detalhes bibliográficos
Main Authors: Becher, Oren J, Holland, Eric C
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195767/
https://ncbi.nlm.nih.gov/pubmed/25061226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489479
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