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Hyperphosphorylation of RPS6KB1, rather than overexpression, predicts worse prognosis in non-small cell lung cancer patients

RPS6KB1 is the kinase of ribosomal protein S6 which is 70 kDa and is required for protein translation. Although the abnormal activation of RPS6KB1 has been found in types of diseases, its role and clinical significance in non-small cell lung cancer (NSCLC) has not been fully investigated. In this st...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Bojiang, Yang, Lan, Zhang, Rui, Gan, Yuncui, Zhang, Wen, Liu, Dan, Chen, Hong, Tang, Huairong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549961/
https://ncbi.nlm.nih.gov/pubmed/28792981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182891
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