A normalization strategy applied to HiCEP (an AFLP-based expression profiling) analysis: Toward the strict alignment of valid fragments across electrophoretic patterns

BACKGROUND: Gene expression analysis based on comparison of electrophoretic patterns is strongly dependent on the accuracy of DNA fragment sizing. The current normalization strategy based on molecular weight markers has limited accuracy because marker peaks are often masked by intense peaks nearby....

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Bibliographic Details
Main Authors: Kadota, Koji, Fukumura, Ryutaro, Rodrigue, Joseph J, Araki, Ryoko, Abe, Masumi
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC554994/
https://ncbi.nlm.nih.gov/pubmed/15748295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-43
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