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Control of RUNX-induced repression of Notch signaling by MLF and its partner DnaJ-1 during Drosophila hematopoiesis

A tight regulation of transcription factor activity is critical for proper development. For instance, modifications of RUNX transcription factors dosage are associated with several diseases, including hematopoietic malignancies. In Drosophila, Myeloid Leukemia Factor (MLF) has been shown to control...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Miller, Marion, Chen, Aichun, Gobert, Vanessa, Augé, Benoit, Beau, Mathilde, Burlet-Schiltz, Odile, Haenlin, Marc, Waltzer, Lucas
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549762/
https://ncbi.nlm.nih.gov/pubmed/28742844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006932
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