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DCTN1 gene analysis in Chinese patients with sporadic amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. Missense mutations of DCTN1 have been identified as a possible genetic risk factor for ALS. Here, we tested the DCTN1 protein-coding exons in 510 sporadic ALS patients in whom SOD1, TARDBP, FUS, and C9orf72 genes were screene...

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Publicado en:PLoS One
Main Authors: Liu, Xiangyi, Yang, Lipeng, Tang, Lu, Chen, Lu, Liu, Xiaolu, Fan, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549744/
https://ncbi.nlm.nih.gov/pubmed/28792508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182572
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